Mouse Ephb6 Antibody

• Background:

  Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2 (By similarity) .

• NCBI Gene ID:

  13848

• Swiss Prot:

  O08644

• Accession Number:

  O08644

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This Mouse Ephb6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 503-530 amino acids from the Central region of mouse Ephb6.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Human, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  110 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  Ephb6

• NCBI Official Name:

  Ephrin type-B receptor 6

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Islam, S., et al. Dig. Dis. Sci. 55 (9) :2478-2488 (2010)

• Background Reference 02:

  Lieben, L., et al. Bone 47 (2) :301-308 (2010)

• Background Reference 03:

  Mordan-McCombs, S., et al. J. Steroid Biochem. Mol. Biol. 121 (1-2), 368-371 (2010) :

• Background Reference 04:

  Zirzow, S., et al. Dev. Biol. 336 (2) :145-155 (2009)

• Other Product Names:

  Ephrin type-B receptor 6, MEP, Tyrosine-protein kinase-defective receptor EPH-6, Ephb6, Cekl

• Tested Applications:

  WB

• Physical Properties:

  Liquid