EPHB4 Antibody

• Background :

  Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.

• NCBI Gene ID :

  2050

• Swiss Prot :

  P54760

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 300-540 of human EPHB4 (NP_004435.3) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Neuroscience, Signal Transduction, Stem Cell

• Purification :

  Affinity purification

• Positive Control :

  Mouse liver

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 108kDa

• Fragment :

  IgG

• Applications Notes :

  WB: 1:200 - 1:2000

• Symbol :

  EPHB4

• NCBI Official Name :

  EPH receptor B4

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  EPHB4, EPH receptor B4, HTK, MYK1, TYRO11, ephrin receptor EphB4, hepatoma transmembrane kinase

• Tested Applications :

  WB

• Physical Properties :

  Liquid