EPHB4 Antibody

CAT: 0223-19-024Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-19-024Size:100 µL
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Background
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development.
NCBI Gene ID
2050
Swiss Prot
P54760
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 300-540 of human EPHB4 (NP_004435.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction, Stem Cell
Purification
Affinity purification
Positive Control
Mouse liver
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 108kDa
Fragment
IgG
Applications Notes
WB: 1:200 - 1:2000
Symbol
EPHB4
NCBI Official Name
EPH receptor B4
NCBI Organism
Homo sapiens
Other Product Names
EPHB4, EPH receptor B4, HTK, MYK1, TYRO11, ephrin receptor EphB4, hepatoma transmembrane kinase
Tested Applications
WB
Physical Properties
Liquid

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