Products for Research Use Only
RegisterLogin

SF3B4 Antibody

CAT: 0223-60-518Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-60-518Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
NCBI Gene ID
10262
Swiss Prot
Q15427
Accession Number
Q15427
Host
Rabbit
Reactivity
Human
Immunogen
This SF3B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 158-187 amino acids from the Central region of human SF3B4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
44 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SF3B4
NCBI Official Name
Splicing factor 3B subunit 4
NCBI Organism
Homo sapiens
Background Reference 01
Gudbjartsson, D.F., et al. Nat. Genet. 40 (5) :609-615 (2008)
Background Reference 02
Rikova, K., et al. Cell 131 (6) :1190-1203 (2007)
Background Reference 03
Watanabe, H., et al. J. Biol. Chem. 282 (28) :20728-20738 (2007)
Background Reference 04
Wu, C., et al. Proteomics 7 (11) :1775-1785 (2007)
Other Product Names
Splicing factor 3B subunit 4, Pre-mRNA-splicing factor SF3b 49 kDa subunit, SF3b50, Spliceosome-associated protein 49, SAP 49, SF3B4, SAP49
Tested Applications
WB
Protein ID
2500587
Physical Properties
Liquid

Related Products

CatalogName
29-232SF3B1 Antibody
29-408SF3B1 Antibody
29-233SF3B1 Antibody
22-031SF3B3 Antibody
19-911SF3B2 Antibody
16-315SF3B5 Antibody
46-363SF3B3 Antibody
57-247SF3B1 Antibody
56-592SF3B3 Antibody
29-428SF3B14 Antibody

Alternative Products

CatalogName
70R-4853SF3B4 antibody

Popular Products