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Mouse Khdrbs1 Antibody

CAT: 0223-60-484Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-484Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.
NCBI Gene ID
20218
Swiss Prot
Q60749
Accession Number
Q60749
Host
Rabbit
Reactivity
Mouse
Immunogen
This Mouse Khdrbs1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-443 amino acids from the C-terminal region of mouse Khdrbs1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Chicken, Human, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
48 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Khdrbs1
NCBI Official Name
KH domain-containing, RNA-binding, signal transduction-associated protein 1
NCBI Organism
Mus musculus
Background Reference 01
Sette, C., et al. J. Androl. 31 (1) :66-74 (2010)
Background Reference 02
Maroni, P., et al. Mol. Cell. Endocrinol. 309 (1-2), 26-31 (2009) :
Background Reference 03
Paronetto, M.P., et al. J. Cell Biol. 185 (2) :235-249 (2009)
Background Reference 04
Huot, M.E., et al. Mol. Cell. Biol. 29 (7) :1933-1943 (2009)
Other Product Names
KH domain-containing, RNA-binding, signal transduction-associated protein 1, GAP-associated tyrosine phosphoprotein p62, Src-associated in mitosis 68 kDa protein, Sam68, p21 Ras GTPase-activating protein-associated p62, p68, Khdrbs1 {ECO:0000312|MGI:MGI:893579}
Tested Applications
WB
Physical Properties
Liquid

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