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KHDRBS1 Antibody

CAT: 0223-29-386Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-29-386Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
KHDRBS1 recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, KHDRBS1 functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. KHDRBS1 play a role in G2-M progression in the cell cycle. It represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. KHDRBS1 also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.
NCBI Gene ID
10657
Swiss Prot
Q07666
Accession Number
NP_006550
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KHDRBS1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cell Cycle, Signal Transduction, Immunology
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10407 - Fetal Heart Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store KHDRBS1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
48 kDa
Applications Notes
KHDRBS1 antibody can be used for detection of KHDRBS1 by ELISA at 1:12500. KHDRBS1 antibody can be used for detection of KHDRBS1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
KHDRBS1
NCBI Official Name
KH domain containing, RNA binding, signal transduction associated 1
NCBI Organism
Homo sapiens
Background Reference 01
Duran, A., (2008) Cancer Cell 13 (4), 343-354.
Other Product Names
KHDRBS1, FLJ34027, Sam68, p62, p68
Tested Applications
ELISA, WB
Protein ID
5730027
Physical Properties
Liquid

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