KHDRBS3 Antibody

• Background:

  As a RNA-binding protein, KHDRBS3 plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. KHDRBS3 may play a role as a negative regulator of cell growth. It inhibits cell proliferation and involved in splice site selection of vascular endothelial growth factor. It induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. It also involved in post-transcriptional regulation of HIV-1 gene expression.

• NCBI Gene ID:

  10656

• Swiss Prot:

  O75525

• Accession Number:

  NP_006549

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KHDRBS3.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store KHDRBS3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  38 kDa

• Applications Notes:

  KHDRBS3 antibody can be used for detection of KHDRBS3 by ELISA at 1:62500. KHDRBS3 antibody can be used for detection of KHDRBS3 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  KHDRBS3

• NCBI Official Name:

  KH domain containing, RNA binding, signal transduction associated 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Cohen, C.D., (2005) J. Am. Soc. Nephrol. 16 (7), 1958-1965.

• Other Product Names:

  KHDRBS3, Etle, SALP, SLM2, SLM-2, TSTAR, T-STAR, etoile

• Tested Applications:

  ELISA, WB, IHC

• Protein ID:

  5730073

• Physical Properties:

  Liquid