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KHDRBS3 Antibody

CAT: 0223-29-385Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-29-385Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
As a RNA-binding protein, KHDRBS3 plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. KHDRBS3 may play a role as a negative regulator of cell growth. It inhibits cell proliferation and involved in splice site selection of vascular endothelial growth factor. It induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. RNA-binding abilities are down-regulated by tyrosine kinase PTK6. It also involved in post-transcriptional regulation of HIV-1 gene expression.
NCBI Gene ID
10656
Swiss Prot
O75525
Accession Number
NP_006549
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KHDRBS3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store KHDRBS3 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
38 kDa
Applications Notes
KHDRBS3 antibody can be used for detection of KHDRBS3 by ELISA at 1:62500. KHDRBS3 antibody can be used for detection of KHDRBS3 by western blot at 0.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
KHDRBS3
NCBI Official Name
KH domain containing, RNA binding, signal transduction associated 3
NCBI Organism
Homo sapiens
Background Reference 01
Cohen, C.D., (2005) J. Am. Soc. Nephrol. 16 (7), 1958-1965.
Other Product Names
KHDRBS3, Etle, SALP, SLM2, SLM-2, TSTAR, T-STAR, etoile
Tested Applications
ELISA, WB, IHC
Protein ID
5730073
Physical Properties
Liquid

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