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KCNE2 Antibody

CAT: 0223-60-422Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-422Size:400 µL
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Background
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a small integral membrane subunit that assembles with the KCNH2 gene product, a pore-forming protein, to alter its function. This gene is expressed in heart and muscle and the gene mutations are associated with cardiac arrhythmia.
NCBI Gene ID
9992
Swiss Prot
Q9Y6J6
Accession Number
Q9Y6J6
Host
Rabbit
Reactivity
Human
Immunogen
This KCNE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-107 amino acids from the C-terminal region of human KCNE2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
14 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
KCNE2
NCBI Official Name
Potassium voltage-gated channel subfamily E member 2
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Albert, C.M., et al. Circ Arrhythm Electrophysiol 3 (3) :222-229 (2010)
Background Reference 03
Subbiah, R.N., et al. CanCardiol 26 (4) :208-212 (2010)
Background Reference 04
Tam, G.W., et al. Biochem. Soc. Trans. 38 (2) :445-451 (2010)
Other Product Names
Potassium voltage-gated channel subfamily E member 2, MinK-related peptide 1, Minimum potassium ion channel-related peptide 1, Potassium channel subunit beta MiRP1, KCNE2
Tested Applications
WB
Protein ID
6685661
Physical Properties
Liquid

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