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KCNB2 Antibody

CAT: 0223-60-604Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-604Size:400 µL
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Background
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog (s) . This gene encodes a member of the potassium channel, voltage-gated, shab-related subfamily. This member is a delayed rectifier potassium channel. The gene is expressed in gastrointestinal smooth muscle cells.
NCBI Gene ID
9312
Swiss Prot
Q92953
Accession Number
Q92953
Host
Rabbit
Reactivity
Human
Immunogen
This KCNB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-166 amino acids from the N-terminal region of human KCNB2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rabbit, Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
103 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
KCNB2
NCBI Official Name
Potassium voltage-gated channel subfamily B member 2
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Cirulli, E.T., et al. Eur. J. Hum. Genet. 18 (7) :815-820 (2010)
Background Reference 03
Baranzini, S.E., et al. Hum. Mol. Genet. 18 (4) :767-778 (2009)
Background Reference 04
Nyholt, D.R., et al. Hum. Mol. Genet. 17 (21) :3318-3331 (2008)
Other Product Names
Potassium voltage-gated channel subfamily B member 2, Voltage-gated potassium channel subunit Kv22, KCNB2
Tested Applications
WB
Protein ID
24418855
Physical Properties
Liquid

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