Mouse Sin3a Antibody

CAT: 0223-60-396Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-60-396Size:400 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Sin3a acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3A to DNA. Acts as a corepressor for REST.
NCBI Gene ID
20466
Swiss Prot
Q60520
Accession Number
Q60520
Host
Rabbit
Reactivity
Mouse
Immunogen
This Mouse Sin3a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1078-1106 amino acids from the C-terminal region of mouse Sin3a.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Human
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
145 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Sin3a
NCBI Official Name
Paired amphipathic helix protein Sin3a
NCBI Organism
Mus musculus
Background Reference 01
Baltus, G.A., et al. J. Biol. Chem. 284 (11) :6998-7006 (2009)
Background Reference 02
Anderson, D.M., et al. Dev. Dyn. 238 (3) :572-580 (2009)
Background Reference 03
Chang, S., et al. J. Immunol. 181 (12) :8372-8381 (2008)
Background Reference 04
Van Oevelen, C., et al. Mol. Cell 32 (3) :359-370 (2008)
Other Product Names
Paired amphipathic helix protein Sin3a, Histone deacetylase complex subunit Sin3a, Transcriptional corepressor Sin3a, Sin3a, Kiaa4126
Tested Applications
WB
Physical Properties
Liquid

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