SIN3B Antibody

• Background :

  SIN3B acts as a transcriptional repressor. It interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also, it interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. The gene is also able to form a complex with FOXK1 which represses transcription

• NCBI Gene ID :

  23309

• Swiss Prot :

  O75182

• Accession Number :

  NP_056075

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SIN3B.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Transcription

• Purification :

  Antibody is purified by peptide affinity chromatography method.

• Positive Control :

  HCT15 Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SIN3B antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  133 kDa

• Applications Notes :

  SIN3B antibody can be used for detection of SIN3B by ELISA at 1:62500. SIN3B antibody can be used for detection of SIN3B by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  SIN3B

• NCBI Official Name :

  SIN3 transcription regulator family member B

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Dhanda, R.S., (er) BMC Mol. Biol. 9, 8 (2008) .

• Other Product Names :

  SIN3B, KIAA0700

• Tested Applications :

  ELISA, WB

• Protein ID :

  52138513

• Physical Properties :

  Liquid