SIN3B Antibody

CAT: 0223-26-549Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-26-549Size:100 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SIN3B acts as a transcriptional repressor. It interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities.It also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. SIN3B also forms a complex with FOXK1 which represses transcription.
NCBI Gene ID
23309
Swiss Prot
O75182
Accession Number
NP_056075
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SIN3B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10123 - Fetal Brain Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SIN3B antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
133 kDa
Applications Notes
SIN3B antibody can be used for detection of SIN3B by ELISA at 1:312500. SIN3B antibody can be used for detection of SIN3B by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SIN3B
NCBI Official Name
SIN3 transcription regulator family member B
NCBI Organism
Homo sapiens
Background Reference 01
Dhanda, R.S., (er) BMC Mol. Biol. 9, 8 (2008) .
Other Product Names
SIN3B, KIAA0700
Tested Applications
ELISA, WB
Protein ID
52138513
Physical Properties
Liquid

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