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CCBL1 Antibody

CAT: 0223-59-946Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-946Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene.
NCBI Gene ID
883
Swiss Prot
Q16773
Accession Number
Q16773
Host
Rabbit
Reactivity
Human
Immunogen
This CCBL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 327-355 amino acids from the C-terminal region of human CCBL1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
48 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CCBL1
NCBI Official Name
Kynurenine--oxoglutarate transaminase 1
NCBI Organism
Homo sapiens
Background Reference 01
Han, Q., et al. J. Med. Chem. 52 (9) :2786-2793 (2009)
Background Reference 02
Cooper, A.J., et al. Arch. Biochem. Biophys. 474 (1) :72-81 (2008)
Background Reference 03
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Background Reference 04
Kapoor, R., et al. Brain Res. 1106 (1) :205-210 (2006)
Other Product Names
Kynurenine--oxoglutarate transaminase 1, Cysteine-S-conjugate beta-lyase, Glutamine transaminase K, GTK, Glutamine--phenylpyruvate transaminase, Kynurenine aminotransferase I, KATI, Kynurenine--oxoglutarate transaminase I, CCBL1
Tested Applications
WB
Protein ID
46396284
Physical Properties
Liquid

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