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CCBE1 Antibody

CAT: 0223-59-070Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-070Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is thought to function in extracellular matrix remodeling and migration. It is predominantly expressed in the ovary, but down regulated in ovarian cancer cell lines and primary carcinomas, suggesting its role as a tumour suppressor. Mutations in this gene have been associated with Hennekam lymphangiectasia-lymphedema syndrome, a generalized lymphatic dysplasia in humans.
NCBI Gene ID
147372
Swiss Prot
Q6UXH8
Accession Number
Q6UXH8
Host
Rabbit
Reactivity
Human
Immunogen
This CCBE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-191 amino acids from the Central region of human CCBE1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
44 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CCBE1
NCBI Official Name
Collagen and calcium-binding EGF domain-containing protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Connell, F., et al. Hum. Genet. 127 (2) :231-241 (2010)
Background Reference 03
Barton, C.A., et al. Br. J. Cancer 102 (1) :87-96 (2010)
Background Reference 04
Alders, M., et al. Nat. Genet. 41 (12) :1272-1274 (2009)
Other Product Names
Collagen and calcium-binding EGF domain-containing protein 1, Full of fluid protein homolog, CCBE1, KIAA1983
Tested Applications
WB
Protein ID
74738220
Physical Properties
Liquid

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