EXTL1 Antibody

• Background:

  This gene is a member of the multiple exostoses (EXT) family of glycosyltransferases, which function in the chain polymerization of heparan sulfate and heparin. The encoded protein harbors alpha 1,4- N-acetylglucosaminyltransferase activity, and is involved in chain elongation of heparan sulfate and possibly heparin.

• NCBI Gene ID:

  2134

• Swiss Prot:

  Q92935

• Accession Number:

  Q92935

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This EXTL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 649-676 amino acids from the C-terminal region of human EXTL1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  75 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  EXTL1

• NCBI Official Name:

  Exostosin-like 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Wu, C., et al. Proteomics 7 (11) :1775-1785 (2007)

• Background Reference 02:

  Mathysen, D., et al. Eur. J. Cancer 40 (8) :1255-1261 (2004)

• Background Reference 03:

  Zak, B.M., et al. Biochim. Biophys. Acta 1573 (3) :346-355 (2002)

• Background Reference 04:

  Kim, B.T., et al. Proc. Natl. Acad. Sci. U.S.A. 98 (13) :7176-7181 (2001)

• Other Product Names:

  Exostosin-like 1, Exostosin-L, Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Multiple exostosis-like protein, EXTL1, EXTL

• Tested Applications:

  WB

• Protein ID:

  93141259

• Physical Properties:

  Liquid