EXT1 Antibody

• Background :

  This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses. [provided by RefSeq].

• NCBI Gene ID :

  2131

• Swiss Prot :

  Q16394

• Accession Number :

  Q16394

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This EXT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-326 amino acids from the Central region of human EXT1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Mouse

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  86 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  EXT1

• NCBI Official Name :

  Exostosin-1

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Zuntini, M., et al. Oncogene 29 (26) :3827-3834 (2010)

• Background Reference 02 :

  Wen, W., et al. Genet Test Mol Biomarkers 14 (3) :371-376 (2010)

• Background Reference 03 :

  Li, Y., et al. Pathology 42 (1) :91-93 (2010)

• Background Reference 04 :

  Baasanjav, S., et al. BMC Med. Genet. 11, 110 (2010) :

• Other Product Names :

  Exostosin-1, Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Multiple exostoses protein 1, Putative tumor suppressor protein EXT1, EXT1

• Tested Applications :

  WB

• Protein ID :

  20141422

• Physical Properties :

  Liquid