EXT1 Antibody

• Background:

  This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses. [provided by RefSeq].

• NCBI Gene ID:

  2131

• Swiss Prot:

  Q16394

• Accession Number:

  Q16394

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This EXT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 298-326 amino acids from the Central region of human EXT1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  86 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  EXT1

• NCBI Official Name:

  Exostosin-1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Zuntini, M., et al. Oncogene 29 (26) :3827-3834 (2010)

• Background Reference 02:

  Wen, W., et al. Genet Test Mol Biomarkers 14 (3) :371-376 (2010)

• Background Reference 03:

  Li, Y., et al. Pathology 42 (1) :91-93 (2010)

• Background Reference 04:

  Baasanjav, S., et al. BMC Med. Genet. 11, 110 (2010) :

• Other Product Names:

  Exostosin-1, Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Multiple exostoses protein 1, Putative tumor suppressor protein EXT1, EXT1

• Tested Applications:

  WB

• Protein ID:

  20141422

• Physical Properties:

  Liquid