EXTL2 Antibody

• Background:

  EXTL2 is a glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.

• NCBI Gene ID:

  2135

• Swiss Prot:

  Q9UBQ6

• Accession Number:

  Q9UBQ6

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This EXTL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-295 amino acids from the C-terminal region of human EXTL2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  37 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  EXTL2

• NCBI Official Name:

  Exostosin-like 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Kaidonis, X., et.al, Eur. J. Hum. Genet. 18 (2), 194-199 (2010)

• Background Reference 02:

  Sobhany, M., et.al, J. Biol. Chem. 280 (25), 23441-23445 (2005)

• Other Product Names:

  Exostosin-like 2, Alpha-1,4-N-acetylhexosaminyltransferase EXTL2, Alpha-GalNAcT EXTL2, EXT-related protein 2, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Processed exostosin-like 2, EXTL2, EXTR2

• Tested Applications:

  WB

• Protein ID:

  9296986

• Physical Properties:

  Liquid