UBE2Q1 Antibody

• Background:

  The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s) . This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is 98% identical to the mouse counterpart.

• NCBI Gene ID:

  55585

• Swiss Prot:

  Q7Z7E8

• Accession Number:

  Q7Z7E8

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This UBE2Q1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-104 amino acids from the N-terminal region of human UBE2Q1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  46 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  UBE2Q1

• NCBI Official Name:

  Ubiquitin-conjugating enzyme E2 Q1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Wassler, M.J., et al. Stem Cells 26 (8) :2006-2018 (2008)

• Background Reference 02:

  Grelle, G., et al. Mol. Cell Proteomics 5 (2) :234-244 (2006)

• Background Reference 03:

  Wistow, G., et al. Mol. Vis. 8, 205-220 (2002) :

• Background Reference 04:

  Marenholz, I., et al. Genome Res. 11 (3) :341-355 (2001)

• Other Product Names:

  Ubiquitin-conjugating enzyme E2 Q1, Protein NICE-5, Ubiquitin carrier protein Q1, Ubiquitin-protein ligase Q1, UBE2Q1, NICE5, UBE2Q

• Tested Applications:

  WB

• Protein ID:

  74750234

• Physical Properties:

  Liquid