MLF1IP Antibody

• Background:

  The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128) . MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]) .

• NCBI Gene ID:

  79682

• Swiss Prot:

  Q71F23

• Accession Number:

  Q71F23

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MLF1IP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-319 amino acids from the C-terminal region of human MLF1IP.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  48 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CENPU

• NCBI Official Name:

  Centromere protein U

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Suzuki, H., et al. Anticancer Res. 27 (3B), 1423-1430 (2007) :

• Background Reference 02:

  Kang, Y.H., et al. Mol. Cell 24 (3) :409-422 (2006)

• Background Reference 03:

  Izuta, H., et al. Genes Cells 11 (6) :673-684 (2006)

• Background Reference 04:

  Okada, M., et al. Nat. Cell Biol. 8 (5) :446-457 (2006)

• Other Product Names:

  Centromere protein U, CENP-U, Centromere protein of 50 kDa, CENP-50, Interphase centromere complex protein 24, KSHV latent nuclear antigen-interacting protein 1, MLF1-interacting protein, Polo-box-interacting protein 1, CENPU, ICEN24, KLIP1, MLF1IP, PBIP1

• Tested Applications:

  WB

• Protein ID:

  74712714

• Physical Properties:

  Liquid