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MLF1 Antibody

CAT: 0223-26-827Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-26-827Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. It interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. MLF1 suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest.It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
NCBI Gene ID
4291
Swiss Prot
P58340
Accession Number
NP_071888
Host
Rabbit
Reactivity
Human
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MLF1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10409 - Fetal Liver Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MLF1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
29 kDa
Applications Notes
MLF1 antibody can be used for detection of MLF1 by ELISA at 1:312500. MLF1 antibody can be used for detection of MLF1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
MLF1
NCBI Official Name
Myeloid leukemia factor 1
NCBI Organism
Homo sapiens
Background Reference 01
Li, Z.F., J. Neurol. Sci. 264 (1-2), 77-86 (2008) .
Other Product Names
MLF1
Tested Applications
ELISA, WB
Protein ID
11967975
Physical Properties
Liquid

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