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NPLOC4 Antibody

CAT: 0223-59-142Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-142Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope (By similarity) .
NCBI Gene ID
55666
Swiss Prot
Q8TAT6
Accession Number
Q8TAT6
Host
Rabbit
Reactivity
Human
Immunogen
This NPLOC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 456-484 amino acids from the C-terminal region of human NPLOC4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
68 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NPLOC4
NCBI Official Name
Nuclear protein localization protein 4 homolog
NCBI Organism
Homo sapiens
Background Reference 01
Liu, F., et al. PLoS Genet. 6, E1000934 (2010) :
Background Reference 02
Lass, A., et al. Exp. Cell Res. 314 (14) :2715-2723 (2008)
Background Reference 03
McConnell, E., et al. Biochem. Biophys. Res. Commun. 355 (4) :1087-1090 (2007)
Background Reference 04
Gevaert, K., et al. Nat. Biotechnol. 21 (5) :566-569 (2003)
Other Product Names
Nuclear protein localization protein 4 homolog, Protein NPL4, NPLOC4, KIAA1499, NPL4
Tested Applications
WB
Protein ID
50428974
Physical Properties
Liquid

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