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WDR68 Antibody

CAT: 0223-59-117Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-117Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
WDR68 is involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity) . Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
NCBI Gene ID
10238
Swiss Prot
P61962
Accession Number
P61962
Host
Rabbit
Reactivity
Human
Immunogen
This WDR68 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-314 amino acids from the C-terminal region of human WDR68.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
39 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
DCAF7
NCBI Official Name
DDB1- and CUL4-associated factor 7
NCBI Organism
Homo sapiens
Background Reference 01
Ritterhoff, S., et al. EMBO J. 29 (22) :3750-3761 (2010)
Background Reference 02
Gudbjartsson, D.F., et al. Nat. Genet. 40 (5) :609-615 (2008)
Background Reference 03
Morita, K., et al. J. Dermatol. Sci. 44 (1) :11-20 (2006)
Background Reference 04
Jin, J., et al. Mol. Cell 23 (5) :709-721 (2006)
Other Product Names
DDB1- and CUL4-associated factor 7, WD repeat-containing protein 68, WD repeat-containing protein An11 homolog, DCAF7, HAN11, WDR68
Tested Applications
WB
Protein ID
48428729
Physical Properties
Liquid

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