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WDR18 Antibody

CAT: 0223-6817-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-6817-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
WDR18 Antibody: WD repeat domain 18 (WDR18) is a member of the WD repeat protein family, which is involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. WD repeats are minimally conserved regions of approximately 40 amino acids that commonly form a tertiary propeller structure. WDR18 is a 432 amino acid protein that contains six WD repeats and is encoded by a gene located on human chromosome 19. WDR18 may play a role during development. The complex PELP1-TEX10-WDR18 is required for the maturation and nucleolar release of the large ribosomal subunit.
NCBI Gene ID
57418
Swiss Prot
Q9BV38
Accession Number
NP_077005
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
WDR18 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1462 - Rat Lung Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (100%)
Buffer
WDR18 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
WDR18 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
WDR18 antibody is predicted to not cross-react with other WDR family members.
Symbol
WDR18
Positive Control 2
Cat. No. 10-101 - Human Lung Tissue Slide
NCBI Official Name
WD repeat domain 1
NCBI Organism
Homo sapiens
Background Reference 01
Smith TF, Gaitatzes C, Saxena K, et al. The WD repeat: a common architecture for diverse functions. Trends Biochem. Sci. 1999; 24:181-5.
Background Reference 02
Gao W, Xu L, Guan R, et al. Wdr18 is required for Kupffer's vesicle formation and regulation of body asymmetry in zebrafish. PLoS One 2011; 6:e23386.
Background Reference 03
Finkbeiner E, Haindl M, and Muller S. The SUMO system controls nucleolar partitioning of a novel mammalian ribosome biogenesis complex. EMBO J. 2011; 30:1067-78.
Other Product Names
WDR18 Antibody: Ipi3, R32184_1, WD repeat-containing protein 18
Tested Applications
ELISA, WB, IHC-P
Protein ID
56243583
Physical Properties
Liquid

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