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Bmp7 Antibody

CAT: 0223-59-010Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-010Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, BMP7 has a proposed role in early development. In addition, the fact that BMP7 is closely related to BMP5 and BMP6 has lead to speculation of possible bone inductive activity.
NCBI Gene ID
655
Swiss Prot
P18075
Accession Number
P18075
Host
Rabbit
Reactivity
Human
Immunogen
This Bmp7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human Bmp7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Cell Cycle, Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
49 kDa
Fragment
Rabbit Ig
Symbol
BMP7
NCBI Official Name
Bone morphogenetic protein 7
NCBI Organism
Homo sapiens
Background Reference 01
Merrihew, C., et al., J. Orthop. Res. 21 (5) :899-907 (2003) .
Background Reference 02
Greenwald, J., et al., Mol. Cell 11 (3) :605-617 (2003) .
Background Reference 03
Maric, I., et al., J. Cell. Physiol. 196 (2) :258-264 (2003) .
Background Reference 04
Im, H.J., et al., J. Biol. Chem. 278 (28) :25386-25394 (2003) .
Other Product Names
Bone morphogenetic protein 7, BMP-7, Osteogenic protein 1, OP-1, Eptotermin alfa, BMP7, OP1
Tested Applications
WB, IHC-P, IF
Protein ID
115078
Physical Properties
Liquid

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