BMP5 Antibody

• Background:

  This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors.

• NCBI Gene ID:

  653

• Swiss Prot:

  P22003

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 317-454 of human BMP5 (NP_066551.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Chemokines & Cytokines, Growth Factors, Immunology, Signal Transduction, Stem Cell

• Purification:

  Affinity purification

• Positive Control:

  H460

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 52kDa

• Fragment:

  IgG

• Symbol:

  BMP5

• Positive Control 2:

  LO2

• Positive Control 3:

  SW620

• Positive Control 4:

  293T

• Positive Control 5:

  Mouse liver

• Positive Control 6:

  Mouse small intestine

• NCBI Official Name:

  Bone morphogenetic protein 5

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  BMP5, bone morphogenetic protein 5, MGC34244

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid