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Bmp6 Antibody

CAT: 0223-59-003Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-003Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, Bmp6 has a proposed role in early development. In addition, the fact that BMP6 is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.
NCBI Gene ID
654
Swiss Prot
P22004
Accession Number
P22004
Host
Rabbit
Reactivity
Human
Immunogen
This Bmp6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-55 amino acids from the N-terminal region of human Bmp6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Cell Cycle, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
57 kDa
Fragment
Rabbit Ig
Symbol
BMP6
NCBI Official Name
Bone morphogenetic protein 6
NCBI Organism
Homo sapiens
Background Reference 01
Lories, R.J., et al., Arthritis Rheum. 48 (10) :2807-2818 (2003) .
Background Reference 02
Bobacz, K., et al., Arthritis Rheum. 48 (9) :2501-2508 (2003) .
Background Reference 03
Tamada, H., et al., Biochim. Biophys. Acta 1395 (3) :247-251 (1998) .
Background Reference 04
Rickard, D.J., et al., J. Clin. Invest. 101 (2) :413-422 (1998) .
Other Product Names
Bone morphogenetic protein 6, BMP-6, VG-1-related protein, VG-1-R, VGR-1, BMP6, VGR
Tested Applications
WB, IHC-P
Protein ID
115076
Physical Properties
Liquid

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