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Bmp5 Antibody

CAT: 0223-58-997Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-997Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Bmp5 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors.
NCBI Gene ID
653
Swiss Prot
P22003
Accession Number
P22003
Host
Rabbit
Reactivity
Human
Immunogen
This Bmp5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human Bmp5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Cell Cycle, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
52 kDa
Fragment
Rabbit Ig
Symbol
BMP5
NCBI Official Name
Bone morphogenetic protein 5
NCBI Organism
Homo sapiens
Background Reference 01
Luo, J., et al., Prostate 51 (3) :189-200 (2002) .
Background Reference 02
Jin, Y., et al., Histol. Histopathol. 16 (4) :1013-1019 (2001) .
Background Reference 03
Sakaue, M., et al., Biochem. Biophys. Res. Commun. 221 (3) :768-772 (1996) .
Background Reference 04
Hahn, G.V., et al., Genomics 14 (3) :759-762 (1992) .
Other Product Names
Bone morphogenetic protein 5, BMP-5, BMP5
Tested Applications
WB, IHC-P
Protein ID
115075
Physical Properties
Liquid

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