RTN1 Antibody

• Background:

  This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. Alternatively spliced transcript variants encoding different isoforms have been identified. Multiple promoters rather than alternative splicing of internal exons seem to be involved in this diversity. [provided by RefSeq].

• NCBI Gene ID:

  6252

• Swiss Prot:

  Q16799

• Accession Number:

  Q16799

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This RTN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-227 amino acids from the N-terminal region of human RTN1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  84 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  RTN1

• NCBI Official Name:

  Reticulon-1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rose, J. Phd, et al. Mol. Med. (2010) In press :

• Background Reference 02:

  Fazi, B., et al. Oncogene 28 (43) :3814-3824 (2009)

• Background Reference 03:

  Melino, S., et al. Biochemistry 48 (2) :242-253 (2009)

• Background Reference 04:

  Di Sano, F., et al. J. Neurochem. 102 (2) :345-353 (2007)

• Other Product Names:

  Reticulon-1, Neuroendocrine-specific protein, RTN1, NSP

• Tested Applications:

  WB

• Protein ID:

  12643733

• Physical Properties:

  Liquid