RTN4 Antibody

RTN4 belongs to the family of reticulons. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. RTN4 is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates.This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified.This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified.

57142

Q9NQC3

NP_997403

Human, Mouse, Rat

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RTN4.

Unconjugated

Primary Antibodies

Membrane, Cancer, Neuroscience, Apoptosis

Antibody is purified by peptide affinity chromatography method.

Cat. No. XBL-10123 - Fetal Brain Tissue Lysate

Batch dependent

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

None

Blue Ice

For short periods of storage (days) store at 4˚ C. For longer periods of storage, store RTN4 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

42 kDa

RTN4 antibody can be used for detection of RTN4 by ELISA at 1:312500. RTN4 antibody can be used for detection of RTN4 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

RTN4

Reticulon 4

Homo sapiens

Hu, F. (2008) J. Neurosci. 28 (5), 1262-1269.

RTN4, ASY, NI220/250, NOGO, NOGO-A, NOGOC, NSP, NSP-CL, Nbla00271, Nbla10545, Nogo-B, Nogo-C, RTN-X, RTN4-A, RTN4-B1, RTN4-B2, RTN4-C

ELISA, WB

47519490