METAP1 Antibody

• Background:

  METAP1 removes the amino-terminal methionine from nascent proteins. Required for normal progression through the cell cycle.

• NCBI Gene ID:

  23173

• Swiss Prot:

  P53582

• Accession Number:

  P53582

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This METAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-216 amino acids from the Central region of human METAP1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Bovine, Chicken

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  43 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  METAP1

• NCBI Official Name:

  Methionine aminopeptidase 1 {ECO:0000255|HAMAP-Rule:MF_03174}

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Xiao, Q., et al. Biochemistry 49 (26) :5588-5599 (2010)

• Background Reference 02:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 03:

  Ross, C.J., et al. Nat. Genet. 41 (12) :1345-1349 (2009)

• Background Reference 04:

  Hu, X.V., et al. Biochemistry 46 (44) :12833-12843 (2007)

• Other Product Names:

  Methionine aminopeptidase 1 {ECO:0000255|HAMAP-Rule:MF_03174}, MAP 1 {ECO:0000255|HAMAP-Rule:MF_03174}, MetAP 1 {ECO:0000255|HAMAP-Rule:MF_03174}, 341118 {ECO:0000255|HAMAP-Rule:MF_03174}, Peptidase M 1 {ECO:0000255|HAMAP-Rule:MF_03174}, METAP1, KIAA0094

• Tested Applications:

  WB

• Protein ID:

  33302602

• Physical Properties:

  Liquid