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P2RX6 Antibody

CAT: 0223-58-955Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-955Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified.
NCBI Gene ID
9127
Swiss Prot
O15547
Accession Number
O15547
Host
Rabbit
Reactivity
Human
Immunogen
This P2RX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the Central region of human P2RX6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
49 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
P2RX6
NCBI Official Name
P2X purinoceptor 6
NCBI Organism
Homo sapiens
Background Reference 01
Trynka, G., et al. Gut 58 (8) :1078-1083 (2009)
Background Reference 02
Luke, M.M., et al. Stroke 40 (2) :363-368 (2009)
Background Reference 03
Palomino-Doza, J., et al. Hypertension 52 (5) :980-985 (2008)
Background Reference 04
Shiffman, D., et al. Arterioscler. Thromb. Vasc. Biol. 28 (1) :173-179 (2008)
Other Product Names
P2X purinoceptor 6, P2X6, ATP receptor, P2XM, Purinergic receptor, Purinergic receptor P2X-like 1, P2RX6, P2RXL1, P2X6
Tested Applications
WB
Physical Properties
Liquid

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