P2RX2 Antibody

• Background:

  The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Six transcript variants encoding six distinct isoforms have been identified for this gene.

• NCBI Gene ID:

  22953

• Swiss Prot:

  Q9UBL9

• Accession Number:

  Q9UBL9

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This P2RX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-109 amino acids from the N-terminal region of human P2RX2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  52 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  P2RX2

• NCBI Official Name:

  P2X purinoceptor 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Allsopp, R.C., et al. J. Biol. Chem. 285 (43) :32770-32777 (2010)

• Background Reference 02:

  Decker, D.A., et al. Neurogastroenterol. Motil. 22 (8) :901-908 (2010)

• Background Reference 03:

  Coddou, C., et al. J. Neurosci. 29 (39) :12284-12291 (2009)

• Background Reference 04:

  Pannek, J., et al. Spinal Cord 47 (7) :561-564 (2009)

• Other Product Names:

  P2X purinoceptor 2, P2X2, ATP receptor, Purinergic receptor, P2RX2, P2X2

• Tested Applications:

  WB

• Protein ID:

  12643353

• Physical Properties:

  Liquid