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PDE7B Antibody

CAT: 0223-55-329Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-55-329Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.
NCBI Gene ID
27115
Swiss Prot
Q9NP56
Accession Number
Q9NP56
Host
Rabbit
Reactivity
Human
Immunogen
This PDE7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 421-450 amino acids from the C-terminal region of human PDE7B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
52 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PDE7B
NCBI Official Name
CAMP-specific 3',5'-cyclic phosphodiesterase 7B
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Kestenbaum, B., et al. J. Am. Soc. Nephrol. 21 (7) :1223-1232 (2010)
Background Reference 03
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34 (5) :800-812 (2010)
Background Reference 04
Ikeda, M., et al. Biol. Psychiatry 67 (3) :263-269 (2010)
Other Product Names
CAMP-specific 3',5'-cyclic phosphodiesterase 7B, PDE7B
Tested Applications
WB
Protein ID
13626185
Physical Properties
Liquid

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