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IQGAP1 Antibody

CAT: 0223-58-784Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-784Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the IQGAP family. The protein contains four IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. Expression of the protein is upregulated by gene amplification in two gastric cancer cell lines.
NCBI Gene ID
8826
Swiss Prot
P46940
Accession Number
P46940
Host
Rabbit
Reactivity
Human
Immunogen
This IQGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256-285 amino acids from the N-terminal region of human IQGAP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
189 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
IQGAP1
NCBI Official Name
Ras GTPase-activating-like protein IQGAP1
NCBI Organism
Homo sapiens
Background Reference 01
Hayashi, H., et al. Int. J. Cancer 126 (11) :2563-2574 (2010)
Background Reference 02
Liang, S., et al. Proteomics 10 (7) :1474-1483 (2010)
Background Reference 03
Nakhaei-Nejad, M., et al. Eur. J. Immunol. 40 (1) :204-213 (2010)
Background Reference 04
Wang, J.B., et al. J. Cell. Sci. 122 (PT 12), 2024-2033 (2009) :
Other Product Names
Ras GTPase-activating-like protein IQGAP1, p195, IQGAP1, KIAA0051
Tested Applications
WB
Protein ID
1170586
Physical Properties
Liquid

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