IQGAP2 Antibody

• Background :

  This gene encodes a member of the IQGAP family. The protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility.

• NCBI Gene ID :

  10788

• Swiss Prot :

  Q13576

• Accession Number :

  Q13576

• Host :

  Rabbit

• Reactivity :

  Human, Mouse

• Immunogen :

  This IQGAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1436-1463 amino acids from the C-terminal region of human IQGAP2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  181 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  IQGAP2

• NCBI Official Name :

  Ras GTPase-activating-like protein IQGAP2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02 :

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 03 :

  Van Laer, L., et al. Eur. J. Hum. Genet. 18 (6) :685-693 (2010)

• Background Reference 04 :

  Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)

• Other Product Names :

  Ras GTPase-activating-like protein IQGAP2, IQGAP2

• Tested Applications :

  WB

• Protein ID :

  292495090

• Physical Properties :

  Liquid