SDCBP2 Antibody

• Background:

  Syntenin 2 binds to the cytoplasmic domains of the syndecans: it contains a tandem repeat of PDZ domains that reacts with the FYA (phe-tyr-ala) C-terminal amino acid sequence of the syndecans. Cells that overexpress the fusion protein show numerous cell surface extensions, suggesting that Syntenin 2 may have an effect on cytoskeleton-membrane organization. Therefore, Syntenin 2 may function as an adaptor that couples syndecans to cytoskeletal proteins or cytosolic downstream signal-effectors.

• NCBI Gene ID:

  27111

• Swiss Prot:

  Q9H190

• Accession Number:

  Q9H190

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SDCBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-127 amino acids from the N-terminal region of human SDCBP2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  32 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SDCBP2

• NCBI Official Name:

  Syntenin-2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345 (3) :1022-1032 (2006)

• Background Reference 02:

  Deloukas, P., et al. Nature 414 (6866) :865-871 (2001)

• Background Reference 03:

  Koroll, M., et al. J. Biol. Chem. 276 (14) :10646-10654 (2001)

• Background Reference 04:

  Borrell-Pages, M., et al. Mol. Biol. Cell 11 (12) :4217-4225 (2000)

• Other Product Names:

  Syntenin-2, Syndecan-binding protein 2, SDCBP2, SITAC18

• Tested Applications:

  WB

• Protein ID:

  20455288

• Physical Properties:

  Liquid