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SDCBP Antibody

CAT: 0223-31-337Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-31-337Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SDCBP was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus.The protein encoded by this gene was initially identified as a molecule linking syndecan-mediated signaling to the cytoskeleton. The syntenin protein contains tandemly repeated PDZ domains that bind the cytoplasmic, C-terminal domains of a variety of transmembrane proteins. This protein may also affect cytoskeletal-membrane organization, cell adhesion, protein trafficking, and the activation of transcription factors. The protein is primarily localized to membrane-associated adherens junctions and focal adhesions but is also found at the endoplasmic reticulum and nucleus. Alternative splicing results in multiple transcript variants encoding different isoforms.
NCBI Gene ID
6386
Swiss Prot
O00560
Accession Number
NP_001007068
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SDCBP.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store SDCBP antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
32 kDa, 32 kDa, 32 kDa, 32 kDa, 32 kDa
Applications Notes
SDCBP antibody can be used for detection of SDCBP by ELISA at 1:312500. SDCBP antibody can be used for detection of SDCBP by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
SDCBP
NCBI Official Name
Syndecan binding protein (syntenin)
NCBI Organism
Homo sapiens
Background Reference 01
Boukerche, H., (2005) Cancer Res. 65 (23), 10901-10911.
Other Product Names
SDCBP, MDA-9, ST1, SYCL, TACIP18
Tested Applications
ELISA, WB, IHC
Protein ID
55749490
Physical Properties
Liquid

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