SDC2 Antibody

• Background:

  The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types.

• NCBI Gene ID:

  6383

• Swiss Prot:

  P34741

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 19-144 of human SDC2 (NP_002989.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Growth Factors, Immunology, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  A-549

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 37kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  SDC2

• Positive Control 2:

  U-251MG

• Positive Control 3:

  HepG2

• Positive Control 4:

  HeLa

• NCBI Official Name:

  Syndecan 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CD362, HSPG, HSPG1, SYND2, syndecan-2, cell surface-associated heparan sulfate proteoglycan 1, fibroglycan, heparan sulfate proteoglycan 1, cell surface-associated, heparan sulfate proteoglycan core protein, syndecan proteoglycan 2

• Tested Applications:

  WB

• Physical Properties:

  Liquid