Products for Research Use Only
RegisterLogin

DIAPH3 Antibody

CAT: 0223-58-585Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-58-585Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
DIAPH3 binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity) .
NCBI Gene ID
81624
Swiss Prot
Q9NSV4
Accession Number
Q9NSV4
Host
Rabbit
Reactivity
Human
Immunogen
This DIAPH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1061-1090 amino acids from the C-terminal region of human DIAPH3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
137 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
DIAPH3
NCBI Official Name
Protein diaphanous homolog 3
NCBI Organism
Homo sapiens
Background Reference 01
DeWard, A.D., et al. J. Biol. Chem. 284 (30) :20061-20069 (2009)
Background Reference 02
Block, J., et al.Microsc 231 (3) :506-517 (2008)
Background Reference 03
Beli, P., et al. Nat. Cell Biol. 10 (7) :849-857 (2008)
Background Reference 04
Yang, C., et al. PLoS Biol. (11), E317 (2007) :
Other Product Names
Protein diaphanous homolog 3, Diaphanous-related formin-3, DRF3, MDia2, DIAPH3, DIAP3
Tested Applications
WB
Protein ID
158520000
Physical Properties
Liquid

Related Products

CatalogName
63-930DIAPH2 Antibody
19-849DIAPH1 Antibody
42-285DIAPH1 Antibody
18-272DIAPH1 Antibody, KO Validated
42-285PDIAPH1 Peptide
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
62-828Neprilysin Antibody
61-580CAPZB Antibody

Alternative Products

CatalogName
70R-16835DIAPH3 antibody

Popular Products