DIAPH1 Antibody, KO Validated

• Background:

  This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

• NCBI Gene ID:

  1729

• Swiss Prot:

  O60610

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1149-1263 of human DIAPH1 (NP_001073280.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Validation:

  Antibody is Knockout validated.

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  293T

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 150kDa

• Fragment:

  IgG

• Symbol:

  DIAPH1

• NCBI Official Name:

  Diaphanous-related formin 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  DIAPH1, diaphanous-related formin 1, diaphanous-1, diaphanous 1, hDIA1, LFHL1, FLJ25265, DRF1, DIA1, DFNA1, diaphanous homolog 1 (Drosophila), DIAPH1, DIAP1

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid