Products for Research Use Only
RegisterLogin

HSD11B1 Antibody

CAT: 0223-26-069Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-26-069Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
HSD11B1 is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, HSD11B1 can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children.The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene.
NCBI Gene ID
3290
Swiss Prot
P28845
Accession Number
NP_005516
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HSD11B1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane, Cancer, Signal Transduction
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10409 - Fetal Liver Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HSD11B1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
32 kDa
Applications Notes
HSD11B1 antibody can be used for detection of HSD11B1 by ELISA at 1:312500. HSD11B1 antibody can be used for detection of HSD11B1 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
HSD11B1
NCBI Official Name
Hydroxysteroid (11-beta) dehydrogenase 1
NCBI Organism
Homo sapiens
Background Reference 01
Paulsen, S.K., (2008) Obesity (Silver Spring) 16 (4), 731-735.
Other Product Names
HSD11B1, 11-DH, 11-beta-HSD1, HDL, HSD11, HSD11B, HSD11L, MGC13539, CORTRD2, SDR26C1
Tested Applications
ELISA, WB
Protein ID
5031765
Physical Properties
Liquid

Related Products

CatalogName
45-748PHSD11B1 Peptide
42-861PHsd11b1 Peptide
64-100HSD11B2 Antibody
13-829HSD17B1 Antibody
55-870HSD11B1L Antibody
58-560HSD17B1 Antibody
29-632HSD17B1 Antibody
25-696HSD11B2 Antibody
23-384HSD11B2 Antibody
62-447HSD17B7 Antibody

Alternative Products

CatalogName
70R-12821HSD11B1 antibody

Popular Products