RAD52 Antibody

• Background:

  The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair.

• NCBI Gene ID:

  5893

• Swiss Prot:

  P43351

• Accession Number:

  P43351

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This RAD52 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-416 amino acids from the C-terminal region of human RAD52.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  46 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  RAD52

• NCBI Official Name:

  DNA repair protein RAD52 homolog

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Liu, Y., et al. Carcinogenesis 31 (10) :1762-1769 (2010)

• Background Reference 02:

  Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press :

• Background Reference 03:

  Briggs, F.B., et al. Am. J. Epidemiol. 172 (2) :217-224 (2010)

• Background Reference 04:

  Liu, C.Y., et al. Carcinogenesis 31 (7) :1259-1263 (2010)

• Other Product Names:

  DNA repair protein RAD52 homolog, RAD52

• Tested Applications:

  WB

• Protein ID:

  1172823

• Physical Properties:

  Liquid