Products for Research Use Only

RAD54 Antibody

CAT: 0223-56-150Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-150Size:400 µL
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Background
The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.
NCBI Gene ID
8438
Swiss Prot
Q92698
Accession Number
Q92698
Host
Rabbit
Reactivity
Human
Immunogen
This RAD54 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 634-663 amino acids from the C-terminal region of human RAD54.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Chicken, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
84 kDa
Fragment
Rabbit Ig
Symbol
RAD54L
NCBI Official Name
DNA repair and recombination protein RAD54-like
NCBI Organism
Homo sapiens
Background Reference 01
Liu, Y., et al. Carcinogenesis 31 (10) :1762-1769 (2010)
Background Reference 02
Briggs, F.B., et al. Am. J. Epidemiol. 172 (2) :217-224 (2010)
Background Reference 03
Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :
Background Reference 04
Guey, L.T., et al. Eur. Urol. 57 (2) :283-292 (2010)
Other Product Names
DNA repair and recombination protein RAD54-like, 364-, RAD54 homolog, hHR54, hRAD54, RAD54L, RAD54A
Tested Applications
WB, Flow
Protein ID
51316508
Physical Properties
Liquid