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POLD3 Antibody

CAT: 0223-58-435Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-435Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The DNA polymerase delta complex is involved in DNA replication and repair, and it consists of the proliferating cell nuclear antigen (PCNA; MIM 176740), the multisubunit replication factor C (see MIM 102579), and the 4 subunit polymerase complex: POLD1 (MIM 174761), POLD2 (MIM 600815), POLD3, and POLD4 (MIM 611525) (Liu and Warbrick, 2006 [PubMed 16934752]) .[supplied by OMIM].
NCBI Gene ID
10714
Swiss Prot
Q15054
Accession Number
Q15054
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This POLD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 416-443 amino acids from the C-terminal region of human POLD3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
POLD3
NCBI Official Name
DNA polymerase delta subunit 3
NCBI Organism
Homo sapiens
Background Reference 01
Michiels, S., et al. Carcinogenesis 30 (5) :763-768 (2009)
Background Reference 02
Baranovskiy, A.G., et al. Cell Cycle 7 (19) :3026-3036 (2008)
Background Reference 03
Baranovskiy, A.G., et al. Acta Crystallogr. Sect.Struct. Biol. Cryst. Commun. 64 (PT 9), 822-824 (2008) :
Background Reference 04
Lemmens, L., et al. Biochem. Biophys. Res. Commun. 367 (2) :264-270 (2008)
Other Product Names
DNA polymerase delta subunit 3, DNA polymerase delta subunit p66, POLD3, KIAA0039
Tested Applications
WB
Protein ID
17375506
Physical Properties
Liquid

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