Mouse Cdk9 Antibody

• Background:

  Member of the cyclin-dependent kinase pair (CDK9/cyclin-T) complex, also called positive transcription elongation factor b (P-TEFb), which facilitates the transition from abortive to production elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAP II), SUPT5H and RDBP. The CDK9/cyclin-K complex has also a kinase activity toward CTD of RNAP II and can substitute for P-TEFb in vitro (By similarity) .

• NCBI Gene ID:

  107951

• Swiss Prot:

  Q99J95

• Accession Number:

  Q99J95

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This Mouse Cdk9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-278 amino acids from the C-terminal region of mouse Cdk9.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Immunology

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  43 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  Cdk9

• NCBI Official Name:

  Cyclin-dependent kinase 9

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Yokoyama, S., et al. Dev. Cell 17 (6) :836-848 (2009)

• Background Reference 02:

  Alarcon, C., et al. Cell 139 (4) :757-769 (2009)

• Background Reference 03:

  Takaya, T., et al. Circ. J. 73 (8) :1492-1497 (2009)

• Background Reference 04:

  Kohoutek, J., et al. Mol. Cell. Biol. 29 (12) :3280-3285 (2009)

• Other Product Names:

  Cyclin-dependent kinase 9, Cell division protein kinase 9, Cdk9

• Tested Applications:

  WB

• Physical Properties:

  Liquid