CDK9 Antibody

• Background:

  The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.

• NCBI Gene ID:

  1025

• Swiss Prot:

  P50750

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 153-372 of human CDK9 (NP_001252.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Immunology, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  A549

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 40kDa

• Fragment:

  IgG

• Symbol:

  CDK9

• Positive Control 2:

  HeLa

• Positive Control 3:

  U-251MG

• Positive Control 4:

  Raji

• Positive Control 5:

  BT-474

• Positive Control 6:

  Mouse spleen

• NCBI Official Name:

  Cyclin-dependent kinase 9

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CDK9, RP11-228B15.5, C-2k, CDC2L4, PITALRE, TAK, CTK1

• Tested Applications:

  WB, IHC, IF, IP

• Physical Properties:

  Liquid