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NR2C1 Antibody

CAT: 0223-58-293Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-293Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined.
NCBI Gene ID
7181
Swiss Prot
P13056
Accession Number
P13056
Host
Rabbit
Reactivity
Human
Immunogen
This NR2C1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 516-545 amino acids from the C-terminal region of human NR2C1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
67 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NR2C1
NCBI Official Name
Nuclear receptor subfamily 2 group C member 1
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Lin, Y.L., et al. Biochem. Biophys. Res. Commun. 350 (2) :430-436 (2006)
Background Reference 03
Li, G., et al. Biochem. Biophys. Res. Commun. 310 (2) :384-390 (2003)
Background Reference 04
Mu, X., et al. Prostate 57 (2) :129-133 (2003)
Other Product Names
Nuclear receptor subfamily 2 group C member 1, Orphan nuclear receptor TR2, Testicular receptor 2, NR2C1, TR2
Tested Applications
WB
Protein ID
226693548
Physical Properties
Liquid

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