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NR2E1 Antibody

CAT: 0223-60-773Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-773Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be required for brain development. May be involved in the regulation of retinal development (By similarity) .
NCBI Gene ID
7101
Swiss Prot
Q9Y466
Accession Number
Q9Y466
Host
Rabbit
Reactivity
Human
Immunogen
This NR2E1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-102 amino acids from the Central region of human NR2E1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Xenopus
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
43 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NR2E1
NCBI Official Name
Nuclear receptor subfamily 2 group E member 1
NCBI Organism
Homo sapiens
Background Reference 01
Liu, H.K., et al. Genes Dev. 24 (7) :683-695 (2010)
Background Reference 02
Iwahara, N., et al. Biochem. Biophys. Res. Commun. 386 (4) :671-675 (2009)
Background Reference 03
De Krom, M., et al. Biol. Psychiatry 65 (7) :625-630 (2009)
Background Reference 04
Kumar, R.A., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 147B (6), 880-889 (2008) :
Other Product Names
Nuclear receptor subfamily 2 group E member 1, Nuclear receptor TLX, Protein tailless homolog, Tll, hTll, NR2E1, TLX
Tested Applications
WB
Protein ID
9910804
Physical Properties
Liquid

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