NR2C2 Antibody

CAT: 0223-60-472Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-60-472Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996 [PubMed 8661150]) .
NCBI Gene ID
7182
Swiss Prot
P49116
Accession Number
P49116
Host
Rabbit
Reactivity
Human
Immunogen
This NR2C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-466 amino acids from the C-terminal region of human NR2C2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
65 kDa
Fragment
Rabbit Ig
Symbol
NR2C2
NCBI Official Name
Nuclear receptor subfamily 2 group C member 2
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Srivastava, R., et al. J. Biol. Chem. 285 (15) :11100-11105 (2010)
Background Reference 03
Ear, T., et al. J. Immunol. 184 (7) :3897-3906 (2010)
Background Reference 04
Suzuki, S., et al. J. Biol. Chem. 285 (7) :4441-4446 (2010)
Other Product Names
Nuclear receptor subfamily 2 group C member 2, Orphan nuclear receptor TAK1, Orphan nuclear receptor TR4, Testicular receptor 4, NR2C2, TAK1, TR4
Tested Applications
WB, IF
Protein ID
1351190
Physical Properties
Liquid

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