NR2C2 Antibody

CAT: 0223-30-342Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-30-342Size:100 µL
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Background
Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes.Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996) .
NCBI Gene ID
7182
Swiss Prot
P49116
Accession Number
NP_003289
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR2C2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Signal Transduction, Neuroscience
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1211 - HepG2 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store NR2C2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
67 kDa
Applications Notes
NR2C2 antibody can be used for detection of NR2C2 by ELISA at 1:312500. NR2C2 antibody can be used for detection of NR2C2 by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
NR2C2
NCBI Official Name
Nuclear receptor subfamily 2, group C, member 2
NCBI Organism
Homo sapiens
Background Reference 01
Lin, W.J., (2003) J. Biol. Chem. 278 (11), 9353-9360.
Other Product Names
NR2C2, TAK1, TR2R1, TR4, hTAK1
Tested Applications
ELISA, WB, IHC
Protein ID
36950991
Physical Properties
Liquid

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