P2RY6 Antibody

• Background:

  The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. Four transcript variants encoding the same isoform have been identified for this gene. [provided by RefSeq].

• NCBI Gene ID:

  5031

• Swiss Prot:

  Q15077

• Accession Number:

  Q15077

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This P2RY6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-314 amino acids from the C-terminal region of human P2RY6.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction, Growth Factors

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  36 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  P2RY6

• NCBI Official Name:

  P2Y purinoceptor 6

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02:

  Ben Yebdri, F., et al. Eur. J. Immunol. 39 (10) :2885-2894 (2009)

• Background Reference 03:

  Wong, A.M., et al. Am. J. Respir. Cell Mol. Biol. 40 (6) :733-745 (2009)

• Background Reference 04:

  Jiang, Y., et al. J. Immunol. 182 (2) :1129-1137 (2009)

• Other Product Names:

  P2Y purinoceptor 6, P2Y6, P2RY6

• Tested Applications:

  WB

• Protein ID:

  2495018

• Physical Properties:

  Liquid